RFSymptoms: Safety netting advice
AdultsHand, foot and mouth disease
DATE LAST REVIEWED: 05/11/2026
When to seek further review
- Arrange GP review if symptoms are not improving after 7 to 10 days.
- Get urgent advice today if a sore mouth prevents drinking, there is less pee or fewer wet nappies, or fever and illness are getting worse.
- Contact a GP if pregnant and affected. Seek advice sooner for a baby, a person with weakened immune defences, or any symptoms causing concern.
- Do not wait for the suggested review time if symptoms become worse, new symptoms appear, or you are worried.
- Contact your GP when the surgery is open. If it is closed, you cannot get the help you need, or you are unsure what to do, call NHS 111. You can call even if you are not sure whether the symptoms are serious.
When to get emergency help
(Immediately dial 999 or go to your nearest Emergency Department)
- A severe headache with a stiff neck, discomfort in bright light, or a rash that does not fade when pressed with a clear glass. Do not wait for a rash to appear.
- Being unable to drink with marked drowsiness, confusion or collapse.
- A seizure or rapidly worsening illness.
- Severe difficulty breathing, such as gasping or being unable to speak normally.
- New confusion or not making sense when speaking.
- Being very difficult to wake.
- Collapse or loss of consciousness.
- Blue, grey, unusually pale or blotchy skin or lips, especially when feeling very unwell.
How to spot sepsis
Sepsis is a life-threatening reaction to an infection. It can get worse quickly. If someone is seriously unwell and may have sepsis, call 999 or go to your nearest Emergency Department. Do not wait for every sign, a high temperature or a rash.
An unwell child under 5 who has not had a pee or wet nappy for 12 hours needs emergency assessment. If you are unsure and there are no emergency signs, call NHS 111 for advice.


Sources
- NHS - Hand, foot and mouth diseasehttps://www.nhs.uk/conditions/hand-foot-mouth-disease/
- NHS - Sepsishttps://www.nhs.uk/conditions/sepsis/
- NHS - When to use NHS 111https://www.nhs.uk/nhs-services/urgent-and-emergency-care-services/when-to-use-111/